Two doses are needed for ages 6 months through age 17, four to eight weeks apart Two doses are needed for ages 18 and up, 28 days apart (or up to six weeks apart, if needed) in the U.S. The bivalent booster can be given at least two months after the last shot. People age 5 and older who have a weakened immune system and have had all recommended doses of a COVID-19 vaccine can get an updated, or bivalent, booster dose of the Pfizer-BioNTech COVID-19 vaccine. People 18 and older may also get a Novavax booster based on the original virus strain six months after their last shot. People can get the booster shot at least two months after their last shot. People age 6 and older can choose between the Pfizer-BioNTech and the Moderna COVID-19 bivalent vaccine booster. People ages 5 and older who had all recommended doses of a COVID-19 vaccine can get the Pfizer-BioNTech COVID-19 updated, or bivalent, booster. An additional primary shot might improve their protection against the COVID-19 virus. People with weakened immune systems might not develop enough immunity after vaccination with two doses of an mRNA COVID-19 vaccine. The CDC recommends an additional primary shot of an mRNA COVID-19 vaccine (at least 28 days after the second dose) for some people age 5 and older with weakened immune systems, such as those who have had an organ transplant. Some protection provided after the first dose Three doses are needed for age 6 months through age 4, with the first two shots given 3 to 8 weeks apart and the third shot at least eight weeks after the second shot Two doses are needed, 21 days apart (or up to six weeks apart, if needed) in the U.S.
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